Emma Frost/White Queen: played by January Jones, Emma is co-leader of the X-Men and the lover of Cyclops. She also seems to have reforged some shadowy alliances from her past, leading the other team members to wonder if they can trust her.
Scott Summers/Cyclops: played by Jensen Ackles, Scott is co-leader of the X-Men and involved with Emma. He is plagued by doubts about his ability to lead the team effectively in the wake of Professor X leaving.
Hank McCoy/Beast: played by Joel Edgerton, Hank fears his continuing mutation will affect his humanity...but not enough to try Dr. Kavita Rao's "miracle cure."
Kitty Pryde/Shadowcat: played by Anna Popplewell, Kitty rejoins the team partly to keep an eye on Emma.
Logan/Wolverine: played by Hugh Jackman, Wolverine...is Wolverine. What is there to say about Wolverine?
Piotr Rasputin/Colossus: played by Andy Whitfield, Piotr was thought dead by all his friends and teammates, but he has returned from the grave in time to have phasingly awesome sex with Kitty. Oops, SPOILER.
Hisako Ichiki/Armor: played by Aoi Yu, Hisako is a new-minted team member (a student, really), who is close to Wolverine.
Cassandra Nova: played by Judi Dench, Nova is Professor X's evil "twin" and the co-leader of the reformed Hellfire Club. She is attempting to destroy the X-Men through Emma Frost.
Sebastian Shaw: played by Guy Pearce, Shaw is co-leader of the Hellfire Club in its current incarnation.
Abigail Brand: played by Katee Sackhoff, Brand is an agent of S.W.O.R.D., a task force which watches and occasionally intervenes in extraterrestrial affairs. She has a thing for furry blue guys.
Ord of the Breakworld: voiced by Ray Stevenson, Ord is an alien from a brutal planet called the Breakworld. The people of his world have a prophecy that one of the X-Men will destroy their world.